LITHUANIAN UNIVERSITY OF HEALTH SCIENCES LUHS LIBRARY REPOSITORY

Cytogenetics : Laboratory work notes

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dc.contributor.author Pečiulaitienė, Nijolė
dc.contributor.author Miceikienė, Ilona Teodora
dc.contributor.author Morkūnienė, Kristina
dc.contributor.author Mišeikienė, Ramutė
dc.contributor.author Baltrėnaitė, Lina
dc.contributor.author Makštutienė, Natalja
dc.contributor.author Smalinskienė, Alina
dc.date.accessioned 2017-08-21T09:18:43Z
dc.date.available 2017-08-21T09:18:43Z
dc.date.issued 2013
dc.identifier.isbn 9789955153160
dc.identifier.uri http://repository.lsmuni.lt/handle/1/145
dc.description.abstract Chromosomes are microscopic structures containing all of an individual's genetic information. The chromosomes are composed of DNA and various proteins. The DNA contains the actual genetic code of an individual, and the proteins protect the DNA and allow the DNA to duplicate properly when the cell divides. Each cell in our body, except for red blood cells, has a nucleus. The chromosomes are contained in this nucleus. Since the chromosomes contain an individual's entire genetic code, every cell contains all the genetic information of an individual. Through a process known as gene expression, only selected portions of the DNA are expressed. Geentic material sometimes can be abnormal. It can be rearranged chromosome material. Sometimes, portions of one chromosome are exchanged with another chromosome. If there is no damage to the genetic information when this exchange occurs, or if the exchange occurred many generations ago and was inherited, the only problems relate to reproduction. When there is a chromosome rearrangement, it is more difficult for the cell to divide the chromosome material equally, i.e. so that each egg or sperm cell has exactly half the genetic material. This may result in a conception in which there is too much or too little genetic material, causing the fetus to develop abnormally. Often when this happens, a miscarriage occurs, and the fetus does not appear to have developed at all. This is sometimes called a blighted ovum. Chromosomes rearrangements are common in tumor cells or in leukemia, and chromosome analysis on the tumor cells or on blood can help in making a correct diagnosis and deciding on appropriate treatment for the condition. Abnormal can also be extra or missing chromosome material. Whenever an individual has too much or too little chromosome material, serious problems are likely to be present. These include birth defects, growth problems, mental retardation, or any combination of the...
dc.description.abstract Laboratorinių darbų aprašai “Citogenetika” skirti užsieniečiams studentams, studijuojantiems “Genetikos” discipliną Veterinarinės medicinos, Veterinarinės maisto saugos, Maisto mokslo, Gyvulininkystės technologijos, Gyvūnų mokslo studijų programose LSMU. Šių laboratorinių darbų pagrindinis tikslas – ugdyti studentų gebėjimus susieti paskaitų metu įgytas teorines žinias su praktiniais užsiėmimais. Apraše pateikta 13 laboratorinių darbų. 1 laboratorinio darbo apraše pateikta kaip paimti kraujo mėginį citogenetiniam tyrimui; 2, 3 ir 4 darbuose aprašomas chromosome kultūros kultivavimas, auginimas ir chromosomų preparatų ruošimas; 5, 6 ir 7 darbuose supažindinama su chromosomų dažymo metodais. Kaip dirbti su optiniu mikroskopu nurodoma 8 darbe. 9 laboratoriniame darbe aprašomas chromosomų vertinimas ir registracija. 10, 11 ir 12 darbuose pateikti ir aprašyti galvijų, arklių ir žmogaus chromosomų rinkiniai, 13 darbe – galvijų chromosome kariotipas. Laboratorinių darbų aprašai pateikti anglų kalba, tekstine forma, iliustruoti paveikslais, lentelėmis.
dc.format.extent 41 p.
dc.language.iso eng
dc.publisher Lietuvos sveikatos mokslų universitetas, Lietuvos akademinė e. biblioteka (eLABa), 20140122
dc.subject Cytogenetics | Laboratory manuals
dc.subject Citogenetika
dc.subject Genetika
dc.title Cytogenetics : Laboratory work notes
dc.type K2c | Mokymo ir metodinė priemonė


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